When considering the drugs most likely to cause former addicts to repeatedly relapse, opioids, cocaine, and methamphetamine ...

Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain.

Researchers have used mouse models to study how cocaine addiction alters the brain, illuminating why relapse is common as ...

Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

I don’t drink anymore. I don’t smoke anymore.” He might have shrugged it off, but reports accumulated in his clinic and ...

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one ...

A new study found GLP-1 drugs were associated with 50% fewer substance-related deaths, 39% fewer drug overdoses, and 26% ...

Drugs commonly prescribed for weight loss and diabetes may offer unexpected benefits in tackling substance abuse, according ...

A popular class of drugs for treating diabetes and obesity reduces addiction, including abuse of alcohol, tobacco, cannabis, opioids and cocaine, according to research published March 4 by researchers ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

Evidence is mounting that the wildly popular weight-loss medicines known as GLP-1s may also hold potential for treating addiction, and the field may be on the verge of obtaining desperately needed ...